resumo
This paper describes the decay kinetics of electrically induced polarization of poly(L-lactic) acid (PLLA) via piezoresponse force microscopy. Two crystalline forms of PLLA (alpha and alpha') were electrically poled at different temperatures (room and above glass transition). Poling at temperatures above glass transition allowed obtaining polarization stable up to 10 days for both forms. This period is enough to trigger and maintain proteins adhesion and cells proliferation, if PLLA is used as a platform for tissue growth. When poled at room temperature, both structures lose polarization after a short time (minutes to hours) being polarization in alpha PLLA stable for longer time. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.4729619]
palavras-chave
STIMULATION; MORPHOLOGY; BEHAVIOR; FUTURE; CELLS
categoria
Physics
autores
Barroca, N; Vilarinho, PM; Fernandes, MHV; Sharma, P; Gruverman, A
nossos autores
Maria Helena Figueira Vaz Fernandes
Professor associado
Natália Braz Barroca
Estudante de doutoramento
Paula Maria Lousada Silveirinha Vilarinho
Vice-DiretorGrupos
2 - nanoestruturas e cerâmicos ferróicos multifuncionais
5 - materiais biomédicos e biomiméticos
agradecimentos
The authors acknowledge the financial support from Luso American Foundation for the Development (FLAD), CICECO, FEDER, QREN, COMPETE, and FCT. Nathalie Barroca is thankful to FCT for the support under the Grant No. SFRH/BD/47331/2008.