Synthesis of hydroxy-7H-benzo[c]fluoren-7-ones

abstract

An efficient synthesis of 2-, 3- and 4-hydroxy-7H-benzo[c] fluoren-7-ones, useful intermediates for the synthesis of photochromic naphthopyrans, is described. The synthetic approach involves the use of oxazolines as activating groups for aromatic nucleophilic substitution and starts with readily available dimethoxynaphthaldehydes.

keywords

PHOTOCHROMIC BEHAVIOR; AROMATIC-SUBSTITUTION; NAPHTHOPYRANS; DERIVATIVES; ACIDS

subject category

Chemistry

authors

Coelho, PJ; Salvador, MA; Oliveira, MM; Carvalho, LM

our authors

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