Stability of electrically induced-polarization in poly (L-lactic) acid for bone regeneration

abstract

This paper describes the decay kinetics of electrically induced polarization of poly(L-lactic) acid (PLLA) via piezoresponse force microscopy. Two crystalline forms of PLLA (alpha and alpha') were electrically poled at different temperatures (room and above glass transition). Poling at temperatures above glass transition allowed obtaining polarization stable up to 10 days for both forms. This period is enough to trigger and maintain proteins adhesion and cells proliferation, if PLLA is used as a platform for tissue growth. When poled at room temperature, both structures lose polarization after a short time (minutes to hours) being polarization in alpha PLLA stable for longer time. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.4729619]

keywords

STIMULATION; MORPHOLOGY; BEHAVIOR; FUTURE; CELLS

subject category

Physics

authors

Barroca, N; Vilarinho, PM; Fernandes, MHV; Sharma, P; Gruverman, A

our authors

acknowledgements

The authors acknowledge the financial support from Luso American Foundation for the Development (FLAD), CICECO, FEDER, QREN, COMPETE, and FCT. Nathalie Barroca is thankful to FCT for the support under the Grant No. SFRH/BD/47331/2008.

Share this project:

Related Publications

We use cookies for marketing activities and to offer you a better experience. By clicking “Accept Cookies” you agree with our cookie policy. Read about how we use cookies by clicking "Privacy and Cookie Policy".