Porphyrin and phthalocyanine glycodendritic conjugates: synthesis, photophysical and photochemical properties

abstract

Synthesis of water soluble porphyrin and phthalocyanine derivatives with, respectively, eight and sixteen galactose units has been carried out. The combined preliminary photophysical and photochemical features of the new products suggest that they might be promising photodynamic therapeutic agents.

keywords

PHOTODYNAMIC THERAPY

subject category

Chemistry

authors

Silva, S; Pereira, PMR; Silva, P; Paz, FAA; Faustino, MAF; Cavaleiro, JAS; Tome, JPC

our authors

acknowledgements

Thanks are due to the University of Aveiro, FCT (Fundacao para a Ciencia e Tecnologia, Portugal) and FEDER for funding the QOPNA, CICECO research units, the Portuguese National NMR Network and the project PTDC/QUI/ 65228/2006. S. Silva, P. Pereira and P. Silva also thank FCT for their post-doctoral, BI and PhD grants: SFRH/BPD/64812/2009, BI/UI55/5457/2011 and SFRH/BD/46601/2008, respectively.

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