Ongoing Supervisions
Bruno Daniel Pinto Morais
PhD Student
Luís Pedro Gomes Monteiro
Research Fellowship
Margarida Menezes Amador Sacramento
Research Fellowship
Vera Catarina Ferreira de Sousa
Research FellowshipProjects
A bioactivated nano-layered hydrogel for dermal regeneration in hard-to-heal ulcers (BioNaNor)
Local CoordinatorOther International
Several strategies have been developed to restore dermal function. These include collagen membranes, decellularized dermis from donors or synthetic graft alternatives. So far, these approaches have been unreliable at best and auto-grafts and transplants (that both create their own problems with donor site morbidity, risk for disease transfer and...Advancing the Regenerative and Translational Potential of Cellular Fibers (CellFi)
PartnerFundação para a Ciência e a Tecnologia
Mesenchymal Stem Cells Scaffold-free Cellular Fibers RegenerationBioengineered autonomous cell-biomaterials devices for generating humanised micro- tissues for regenerative medicine (ATLAS)
CoordinatorEuropean Comission
New generations of devices for tissue engineering (TE) should rationalize better the physical and biochemical cues operating in tandem during native regeneration, in particular at the scale/organizational-level of the stem cell niche. The understanding and the deconstruction of these factors (e.g. multiple cell types exchanging both paracrine an...Bioinspired tile-matching to create ultrastructured bone microtissues in a close-to-native fashion (TETRISSUE)
PartnerFundação para a Ciência e a Tecnologia
endochondral ossification modular tissue engineering mechanobiology 3D co-culturesBiorrefinaria de microalgas Coccolithophore: uma abordagem para biomateriais sustentaveis (Coccolitho4BioMat)
PartnerFundação para a Ciência e a Tecnologia
BlueGlue: Bioinspired medical adhesives from marine macroalgae derived biopolymers (BLUEGLUE)
CoordinatorOther National
BLUEGLUE project aims to value and promote the sustainable and controlled production of macroalgae, a way that they can be certified and used into the development of products with high added value (biomedical products). The project is aligned with the structures of the circular and biological economy and aims to provide a boost to the emerging i...Cápsulas esféricas multicompartimentalizadas de alto rendimento para a transplantação de co-culturas multimodais de células estaminais derivadas do tecido adiposo e ilhotas pancreáticas. (TranSphera)
PartnerFundação para a Ciência e a Tecnologia
Colonizacao 3D de celulas em hidrogeis de origem marinha atraves de padronizacao por microcanais para regeneracao ossea (PROMENADE)
PartnerFundação para a Ciência e a Tecnologia
Desenvolvimento de hidrogeis de inspiracao marinha multifuncionais e de elevado desempenho para regeneracao de cartilagem, reticulados com ligacoes nao-covalentes e bio-instrutivas deslizantes. (MARGEL)
CoordinatorFundação para a Ciência e a Tecnologia
Desenvolvimento de uma membrana periodontal multicamada composta por blocos inovativos a base de polimeros de origem marinha e enzima para regeneracao guiada de osso que possui mineralizacao enzimatica controlada. (MIMETIc)
PartnerFundação para a Ciência e a Tecnologia
Development of 4D wireless thermometry to target tumor ablation (PTDC/NAN-MAT/3901/2020)
PartnerFundação para a Ciência e a Tecnologia
Thermography Magnetic Nanoparticles Induced Hyperthermia BioprintingDispositivos Supramoleculares Auto-Regulados baseados na Complementaridade dos Pares de Base do ADN: Uma Tecnologia Biomimética e com Reconheciemnto Molecular para Isolar Células Específicas para Aplicações Biomédicas (SUPRASORT)
PartnerFundação para a Ciência e a Tecnologia
Enabling precision chemical methodologies applied to natural -based systems for the development of multifunctional biomedical devices (CHEM2NATURE)
Local CoordinatorEuropean Comission
CHEM2NATURE addresses current limitations of UMINHO in the Chemistry field regarding its scientific know-how and partnerships with world-leading institutions. UMINHO seeks to improve the multifunctionality of natural-origin polymers, often with limited bioactivity and stimuli-responsiveness, and increase the performance of cell-based therapies. ...European Network of Bioadhesion Expertise: Fundamental Knowledge to Inspire Advanced Bonding Technologies (COST Action CA15216)
Local CoordinatorEuropean Comission
Many organisms, ranging from bacteria and fungi to those much larger animals and plants use chemical and mechanical means to attach permanently or temporarily to surfaces. Some bioadhesives have advantages over synthetic counterparts in terms of their ability to function over a wide temperature range, in wet or dry environments, and to form stab...Extracellular matrix derived products from human placenta to engineer bone microtissues for in vitro disease models (AMNIOGEL)
CoordinatorEuropean Comission
Hidrogéis de Lisados de Plaquetas para Regeneração do Miocárdio (BEAT)
PartnerFundação para a Ciência e a Tecnologia
Human Platelet Lysates-based Scaffolds for Interfacial Multi-tissue Repair (INTERLYNK)
CoordinatorEuropean Comission
InterLynk aims to develop multi-tissue 3D patient-specific scaffolds by providing a portfolio of highly compatible and biofunctional composite inks and biomaterials, and streamlining their co-processing using an upgraded AM equipment. Unprecedented biofunctionality in the synthetic reconstruction of complex interfacial tissues is expected to be ...Hydralazine: Testing an off-label effect in Castration-Resistant Prostate Cancer (HyTherCaP)
Local CoordinatorFundação para a Ciência e a Tecnologia
Prostate cancer (PCa) is one of the most commonly diagnosed malignancies worldwide and a leading cause of cancer-related deaths among men. In Portugal, it is the most incident cancer and the 3rd cause of death (1, 2). Although most of PCa are clinically indolent, a variable proportion of patients develop castration-resistant PCa (CRPC), an aggre...Marine Origin Biopolymers as Innovative Building Blocks from the Sea for the Development of Bioresorbable Multilayered Membranes for guided bone regeneration (BLUETEETH)
CoordinatorFundação para a Ciência e a Tecnologia
Natural origin polymers from algae and arthropods can be obtained in large scale, and a great effort has been paid to find applications for such high-added value materials. Periodontal disease is frequent in humans and constitutes, together with dental caries, the principal cause of tooth loss in adults. Currently, one of the available treatment...Metodologias eficientes para a conjugação de polissacarídeos naturais com péptidos para obtenção de membranas multifuncionais para regeneração periodontal. (COP2P)
PartnerFundação para a Ciência e a Tecnologia
Novel 3D platforms to engineer bone microtissues for in vitro disease models (Microbone)
CoordinatorEuropean Comission
Osteosarcoma is a rare but devastating bone tumour that mainly affects children, adolescents and elderly. This type of tumour is very resistant to therapy, being thus urgent to find new effective treatments. In vitro tumour models can recapitulate many aspects of the natural tumour environment, and could be used to improve the predictive value o...Produção de Plataformas Microcapsulares 3D+ para Avaliação Laboratorial em Larga Escala de Novas Terapias Combinatórias para o Cancro do Pâncreas (PANGEIA)
PartnerFundação para a Ciência e a Tecnologia
Regeneração Óssea Orquestrada pela Interação de Células do Sistema Imunitário com Microlaboratórios de Células e Microplataformas Padronizadas (CIRCUS)
PartnerFundação para a Ciência e a Tecnologia
Tailored Elastin-like Recombinamers as Advanced Systems for Cell Therapies in Diabetes Mellitus:a Synthetic Biology Approach towards a Bioeffective and Immunoisolated Biosimilar Islet/Cell Niche (ELASTISLET)
Local CoordinatorEuropean Comission
ELASTISLET aims to create a breakthrough development in encapsulation technology and its use in cell and tissue therapies for the treatment of type 1 and 2 diabetes. ELASTISLET will combine leading technologies in biomaterial design, production and processing, cross-linking/grafting technology and cell therapy, to synergistically integrate them ...Publications
Recent advances in the design of implantable insulin secreting heterocellular islet organoids
M. Birgul Akolpoglu, Yasemin Inceoglu, Ugur Bozuyuk, Ana Rita Sousa, Mariana B. Oliveira, João F. Mano, Seda Kizilel
2021, Biomaterials, 269, 120627.
Engineering Strategies for Allogeneic Solid Tissue Acceptance
A.R. Sousa, J.F. Mano, M.B. Oliveira
2021, Trends in Molecular Medicine.
One-Step Rapid Fabrication of Cell-Only Living Fibers
Sousa, AR; Martins-Cruz, C; Oliveira, MB; Mano, JF
2020, ADVANCED MATERIALS, 32, 2.
ISBN:
1521-4095
Multi-layer pre-vascularized magnetic cell sheets for bone regeneration
Silva, AS; Santos, LF; Mendes, MC; Mano, JF
2020, BIOMATERIALS, 231.
ISBN:
1878-5905
Human Platelet Lysates-Based Hydrogels: A Novel Personalized 3D Platform for Spheroid Invasion Assessment
Monteiro, CF; Santos, SC; Custodio, CA; Mano, JF
2020, ADVANCED SCIENCE, 7, 7.
ISBN:
2198-3844
Advanced Bottom-Up Engineering of Living Architectures
Gaspar, VM; Lavrador, P; Borges, J; Oliveira, MB; Mano, JF
2020, ADVANCED MATERIALS, 32, 6.
ISBN:
1521-4095
Bioactive silica nanoparticles with calcium and phosphate for single dose osteogenic differentiation
Tavares, MT; Oliveira, MB; Mano, JF; Farinha, JPS; Baleizao, C
2020, MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 107.
ISBN:
1873-0191
Biomedical applications of laminarin
Zargarzadeh, M; Amaral, AJR; Custodio, CA; Mano, JF
2020, CARBOHYDRATE POLYMERS, 232.
ISBN:
1879-1344
Cell Behavior within Nanogrooved Sandwich Culture Systems
Bjorge, IM; Salmeron-Sanchez, M; Correia, CR; Mano, JF
2020, SMALL, 16, 31.
ISBN:
1613-6829
Cell Encapsulation Systems Toward Modular Tissue Regeneration: From Immunoisolation to Multifunctional Devices
Correia, CR; Nadine, S; Mano, JF
2020, ADVANCED FUNCTIONAL MATERIALS, 30, 26.
ISBN:
1616-3028
Coffee Melanoidin-Based Multipurpose Film Formation: Application to Single-Cell Nanoencapsulation
Kim, JY; Kim, S; Han, S; Han, SY; Passos, CP; Seo, J; Lee, H; Kang, EK; Mano, JF; Coimbra, MA; Park, JH; Choi, IS
2020, CHEMNANOMAT, 6, 3, 379-385.
Designing multigradient biomaterials for skin regeneration
Rahmati, M; Blaker, JJ; Lyngstadaas, SP; Mano, JF; Haugen, HJ
2020, MATERIALS TODAY ADVANCES, 5.
Dynamic microfactories co-encapsulating osteoblastic and adipose-derived stromal cells for the biofabrication of bone units
Nadine, S; Patricio, SG; Correia, CR; Mano, JF
2020, BIOFABRICATION, 12, 1.
ISBN:
1758-5090
Enzymatically degradable, starch-based layer-by-layer films: application to cytocompatible single-cell nanoencapsulation
Moon, HC; Han, S; Borges, J; Pesqueira, T; Choi, H; Han, SY; Cho, H; Park, JH; Mano, JF; Choi, IS
2020, SOFT MATTER, 16, 26, 6063-6071.
ISBN:
1744-6848
Extraction and Physicochemical Characterization of Chitin from Cicada orni Sloughs of the South-Eastern French Mediterranean Basin
Poerio, A; Petit, C; Jehl, JP; Arab-Tehrany, E; Mano, JF; Cleymand, F
2020, MOLECULES, 25, 11.
ISBN:
1420-3049
Fabrication of Artificial Nanobasement Membranes for Cell Compartmentalization in 3D Tissues
Zeng, JF; Sasaki, N; Correia, CR; Mano, JF; Matsusaki, M
2020, SMALL, 16, 24.
ISBN:
1613-6829
Freeform 3D printing using a continuous viscoelastic supporting matrix
Patricio, SG; Sousa, LR; Correia, TR; Gaspar, VM; Pires, LS; Luis, JL; Oliveira, JM; Mano, JF
2020, BIOFABRICATION, 12, 3.
ISBN:
1758-5090
Hydrogel 3D in vitro tumor models for screening cell aggregation mediated drug response
Monteiro, MV; Gaspar, VM; Ferreira, LP; Mano, JF
2020, BIOMATERIALS SCIENCE, 8, 7, 1855-1864.
ISBN:
2047-4849
Injectable Biomaterials for Dental Tissue Regeneration
Haugen, HJ; Basu, P; Sukul, M; Mano, JF; Reseland, JE
2020, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21, 10.
ISBN:
1422-0067
Mechanochemical Patternable ECM-Mimetic Hydrogels for Programmed Cell Orientation
Lavrador, P; Gaspar, VM; Mano, JF
2020, ADVANCED HEALTHCARE MATERIALS, 9, 10.
ISBN:
2192-2659
Novel Biodegradable Laminarin Microparticles for Biomedical Applications
Castanheira, EJ; Correia, TR; Rodrigues, JMM; Mano, JE
2020, BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 93, 6, 713-719.
ISBN:
1348-0634
Perinatal tissues and cells in tissue engineering and regenerative medicine
Deus, IA; Mano, JF; Custodio, CA
2020, ACTA BIOMATERIALIA, 110, 1-14.
ISBN:
1878-7568
Recent progresses in the adsorption of organic, inorganic, and gas compounds by MCM-41-based mesoporous materials
Costa, JAS; de Jesus, RA; Santos, DO; Mano, JF; Romao, LPC; Paranhos, CM
2020, MICROPOROUS AND MESOPOROUS MATERIALS, 291.
ISBN:
1873-3093
Repurposing Old Drugs into New Epigenetic Inhibitors: Promising Candidates for Cancer Treatment?
Moreira-Silva, F; Camilo, V; Gaspar, V; Mano, JE; Henrique, R; Jeronimo, C
2020, PHARMACEUTICS, 12, 5.
ISBN:
1999-4923
Responsive laminarin-boronic acid self-healing hydrogels for biomedical applications
Amaral, AJR; Gaspar, VM; Mano, JF
2020, POLYMER JOURNAL, 52, 8, 997-1006.
ISBN:
1349-0540
Role of active nanoliposomes in the surface and bulk mechanical properties of hybrid hydrogels
Kadri, R; Bacharouch, J; Elkhoury, K; Ben Messaoud, G; Kahn, C; Desobry, S; Linder, M; Tamayol, A; Francius, G; Mano, JF; Sanchez-Gonzalez, L; Arab-Tehrany, E
2020, MATERIALS TODAY BIO, 6.
Self-Assembled Bioactive Colloidal Gels as Injectable Multiparticle Shedding Platforms
Freitas, B; Lavrador, P; Almeida, RJ; Gaspar, VM; Mano, JF
2020, ACS APPLIED MATERIALS & INTERFACES, 12, 28, 31282-31291.
ISBN:
1944-8252
Thin Silica-Based Microsheets with Controlled Geometry
Maciel, MM; Patricio, SG; Borges, J; Levkin, PA; Correia, TR; Mano, JF
2020, EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2020, 17, 1574-1578.
ISBN:
1099-0682
Complex-shaped magnetic 3D cell-based structures for tissue engineering
Santos, LF; Silva, AS; Mano, JF
2020, ACTA BIOMATERIALIA, 118, 18-31.
ISBN:
1878-7568
Leachable-Free Fabrication of Hydrogel Foams Enabling Homogeneous Viability of Encapsulated Cells in Large-Volume Constructs
Salvador, T; Oliveira, MB; Mano, JF
2020, ADVANCED HEALTHCARE MATERIALS, 9, 20.
ISBN:
2192-2659
Modeling of Cell-Mediated Self-Assembled Colloidal Scaffolds
Dias, CS; Custodio, CA; Antunes, GC; da Gama, MMT; Mano, JF; Araujo, NAM
2020, ACS APPLIED MATERIALS & INTERFACES, 12, 43, 48321-48328.
ISBN:
1944-8252
Decellularized Extracellular Matrix for Bioengineering Physiomimetic 3D in Vitro Tumor Models
Ferreira, LP; Gaspar, VM; Mano, JF
2020, TRENDS IN BIOTECHNOLOGY, 38, 12, 1397-1414.
ISBN:
1879-3096
Efficient Single-Dose Induction of Osteogenic Differentiation of Stem Cells Using Multi-Bioactive Hybrid Nanocarriers
Tavares, MT; Oliveira, MB; Gaspar, VM; Mano, JF; Farinha, JPS; Baleizao, C
2020, ADVANCED BIOSYSTEMS, 4, 11.
ISBN:
2366-7478
Geometrically Controlled Liquefied Capsules for Modular Tissue Engineering Strategies
Nadine, S; Patricio, SG; Barrias, CC; Choi, IS; Matsusaki, M; Correia, CR; Mano, JF
2020, ADVANCED BIOSYSTEMS, 4, 11.
ISBN:
2366-7478
Curcumin Loaded Nanoliposomes Localization by Nanoscale Characterization
Arab-Tehrany, E; Elkhoury, K; Francius, G; Jierry, L; Mano, JF; Kahn, C; Linder, M
2020, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21, 19.
ISBN:
1422-0067
Differential Modulation of the Phospholipidome of Proinflammatory Human Macrophages by the Flavonoids Quercetin, Naringin and Naringenin
Conde, TA; Mendes, L; Gaspar, VM; Mano, JF; Melo, T; Domingues, MR; Duarte, IF
2020, MOLECULES, 25, 15.
ISBN:
1420-3049
Antibacterial free-standing polysaccharide composite films inspired by the sea
Vale, AC; Pereira, P; Barbosa, AM; Torrado, E; Mano, JF; Alves, NM
2019, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 133, 933-944.
ISBN:
1879-0003
Recent advances on open fluidic systems for biomedical applications: A review
Oliveira, NM; Vilabril, S; Oliveira, MB; Reis, RL; Mano, JF
2019, MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 97, 851-863.
ISBN:
1873-0191
Physical immobilization of particles inspired by pollination
Santos, LF; Silva, AS; Correia, CR; Mano, JF
2019, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 116, 12, 5405-5410.
Temperature-responsive nanomagnetic logic gates for cellular hyperthermia
Silva, RO; Pereira, RA; Silva, FM; Gaspar, VM; Ibarra, A; Millan, A; Sousa, FL; Mano, JF; Silva, NJO
2019, MATERIALS HORIZONS, 6, 3, 524-530.
ISBN:
2051-6355
Oxidized Cashew Gum Scaffolds for Tissue Engineering
Maciel, JS; Azevedo, S; Correia, CR; Costa, AMS; Costa, RR; Magalhaes, FA; Monteiro, AADS; Costa, JFG; de Paula, RCM; Feitosa, JPA; Mano, JF
2019, MACROMOLECULAR MATERIALS AND ENGINEERING, 304, 3.
ISBN:
1439-2054
3D collagen microfibers stimulate the functionality of preadipocytes and maintain the phenotype of mature adipocytes for long term cultures
Louis, F; Kitano, S; Mano, JF; Matsusaki, M
2019, ACTA BIOMATERIALIA, 84, 194-207.
ISBN:
1878-7568
Flavonoid-mediated immunomodulation of human macrophages involves key metabolites and metabolic pathways
Mendes, LF; Gaspar, VM; Onde, TAC; Mano, JF; Duarte, IF
2019, SCIENTIFIC REPORTS, 9.
Liquefied Microcapsules as Dual-Microcarriers for 3D+3D Bottom-Up Tissue Engineering
Correia, CR; Bjorge, IM; Zeng, JF; Matsusaki, M; Mano, JF
2019, ADVANCED HEALTHCARE MATERIALS, 8, 22.
ISBN:
2192-2659
Nanogrooved microdiscs for bottom-up modulation of osteogenic differentiation
Bjorge, IM; Choi, IS; Correia, CR; Mano, JF
2019, NANOSCALE, 11, 35, 16214-16221.
ISBN:
2040-3372
Screening of perfused combinatorial 3D microenvironments for cell culture
Lopes, D; Fernandes, C; Nobrega, JM; Patricio, SG; Oliveira, MB; Mano, JF
2019, ACTA BIOMATERIALIA, 96, 222-236.
ISBN:
1878-7568
Status and future scope of plant-based green hydrogels in biomedical engineering
Mohammadinejad, R; Maleki, H; Larraneta, E; Fajardo, AR; Nik, AB; Shavandi, A; Sheikhi, A; Ghorbanpour, M; Farokhi, M; Govindh, P; Cabane, E; Azizi, S; Aref, AR; Mozafari, M; Mehrali, M; Thomas, S; Mano, JF; Mishra, YK; Thakur, VK
2019, APPLIED MATERIALS TODAY, 16, 213-246.
Microparticles in Contact with Cells: From Carriers to Multifunctional Tissue Modulators
Neto, MD; Oliveira, MB; Mano, JF
2019, TRENDS IN BIOTECHNOLOGY, 37, 9, 1011-1028.
ISBN:
1879-3096
Supramolecular Presentation of Hyaluronan onto Model Surfaces for Studying the Behavior of Cancer Stem Cells
Pang, XQ; O'Malley, C; Borges, J; Rahman, MM; Collis, DWP; Mano, JF; Mackenzie, IC; Azevedo, HS
2019, ADVANCED BIOSYSTEMS, 3, 10.
ISBN:
2366-7478
In-air production of 3D co-culture tumor spheroid hydrogels for expedited drug screening
Antunes, J; Gaspar, VM; Ferreira, L; Monteiro, M; Henrique, R; Jeronimo, C; Mano, JF
2019, ACTA BIOMATERIALIA, 94, 392-409.
ISBN:
1878-7568
Surface Micro- and Nanoengineering: Applications of Layer-by-Layer Technology as a Versatile Tool to Control Cellular Behavior
Sousa, MP; Arab-Tehrany, E; Cleymand, F; Mano, JF
2019, SMALL, 15, 30.
ISBN:
1613-6829
Cell encapsulation in liquified compartments: Protocol optimization and challenges
Correia, CR; Ghasemzadeh-Hasankolaei, M; Mano, JF
2019, PLOS ONE, 14, 6.
Mechanical Properties of Ca-Saturated Hydrogels with Functionalized Alginate
Dalheim, MO; Omtvedt, LA; Bjorge, IM; Akbarzadeh, A; Mano, JF; Aachmann, FL; Strand, BL
2019, GELS, 5, 2.
ISBN:
2310-2861
Bioactive Glass-Polymer Nanocomposites for Bone Tissue Regeneration Applications: A Review
Erol-Taygun, M; Unalan, I; Idris, MIB; Mano, JF; Boccaccini, AR
2019, ADVANCED ENGINEERING MATERIALS, 21, 8.
ISBN:
1527-2648
Three-Dimensional Osteosarcoma Models for Advancing Drug Discovery and Development
Monteiro, CF; Custodio, CA; Mano, JF
2019, ADVANCED THERAPEUTICS, 2, 3.
ISBN:
2366-3987
Blood Plasma Derivatives for Tissue Engineering and Regenerative Medicine Therapies
Santos, SC; Sigurjonsson, OE; Custódio, CA; Mano, JF
2018, Tissue Engineering Part B - Reviews, 24, 6, 454-462.
Biomaterials for drug delivery patches
Santos, LF; Correia, IJ; Silva, AS; Mano, JF
2018, EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 118, 49-66.
Patterned superhydrophobic surfaces to process and characterize biomaterials and 3D cell culture
Neto, AI; Levkin, PA; Mano, JF
2018, MATERIALS HORIZONS, 5, 3, 379-393.
Strategic Advances in Formation of Cell-in-Shell Structures: From Syntheses to Applications
Kim, BJ; Cho, H; Park, JH; Mano, JF; Choi, IS
2018, ADVANCED MATERIALS, 30, 14.
Nanostructured Biopolymer/Few-Layer Graphene Freestanding Films with Enhanced Mechanical and Electrical Properties
Silva, C; Caridade, SG; Cunha, E; Sousa, MP; Rocha, H; Mano, JF; Paiva, MC; Alves, NM
2018, MACROMOLECULAR MATERIALS AND ENGINEERING, 303, 4.
Adhesive free-standing multilayer films containing sulfated levan for biomedical applications
Gomes, TD; Caridade, SG; Sousa, MP; Azevedo, S; Kandur, MY; Oner, ET; Alves, NM; Mano, JF
2018, ACTA BIOMATERIALIA, 69, 183-195.
Stimuli-responsive nanocarriers for delivery of bone therapeutics - Barriers and progresses
Lavrador, P; Gaspar, VM; Mano, JF
2018, JOURNAL OF CONTROLLED RELEASE, 273, 51-67.
Preparation of Well-Dispersed Chitosan/Alginate Hollow Multilayered Microcapsules for Enhanced Cellular Internalization
Ribeiro, C; Borges, J; Costa, AMS; Gaspar, VM; Bermudez, VD; Mano, JF
2018, MOLECULES, 23, 3.
Photopolymerizable Platelet Lysate Hydrogels for Customizable 3D Cell Culture Platforms
Santos, SC; Custodio, CA; Mano, JF
2018, ADVANCED HEALTHCARE MATERIALS, 7, 23.
Bioinspired bone therapies using naringin: applications and advances
Lavrador, P; Gaspar, VM; Mano, JF
2018, DRUG DISCOVERY TODAY, 23, 6, 1293-1304.
Bioinstructive Naringin-Loaded Micelles for Guiding Stem Cell Osteodifferentiation
Lavrador, P; Gaspar, VM; Mano, JF
2018, ADVANCED HEALTHCARE MATERIALS, 7, 19.
Multifunctional laminarin microparticles for cell adhesion and expansion
Martins, CR; Custodio, CA; Mano, JF
2018, CARBOHYDRATE POLYMERS, 202, 91-98.
Bioinstructive microparticles for self-assembly of mesenchymal stem Cell-3D tumor spheroids
Ferreira, LP; Gaspar, VM; Mano, JF
2018, BIOMATERIALS, 185, 155-173.
Bone physiology as inspiration for tissue regenerative therapies
Lopes, D; Martins-Cruz, C; Oliveira, MB; Mano, JF
2018, BIOMATERIALS, 185, 240-275.
Bioactive Hydrogel Marbles
Leite, AJ; Oliveira, NM; Song, WL; Mano, JF
2018, SCIENTIFIC REPORTS, 8.
Design Principles and Multifunctionality in Cell Encapsulation Systems for Tissue Regeneration
Correia, CR; Reis, RL; Mano, JF
2018, ADVANCED HEALTHCARE MATERIALS, 7, 19.
Tuneable spheroidal hydrogel particles for cell and drug encapsulation
Bjorge, IM; Costa, AMS; Silva, AS; Vidal, JPO; Norega, JM; Mano, JF
2018, SOFT MATTER, 14, 27, 5622-5627.
Design of spherically structured 3D in vitro tumor models -Advances and prospects
Ferreira, LP; Gaspar, VM; Mano, JF
2018, ACTA BIOMATERIALIA, 75, 11-34.
Strontium-Doped Bioactive Glass Nanoparticles in Osteogenic Commitment
Leite, AJ; Goncalves, AI; Rodrigues, MT; Gomes, ME; Mano, JF
2018, ACS APPLIED MATERIALS & INTERFACES, 10, 27, 23311-23320.
Bioinspired multilayer membranes as potential adhesive patches for skin wound healing
Sousa, MP; Neto, AI; Correia, TR; Miguel, SP; Matsusaki, M; Correia, IJ; Mano, JF
2018, BIOMATERIALS SCIENCE, 6, 7, 1962-1975.
Sequentially Moldable and Bondable Four-Dimensional Hydrogels Compatible with Cell Encapsulation
Oliveira, MB; Bastos, HXS; Mano, JF
2018, BIOMACROMOLECULES, 19, 7, 2742-2749.
Coculture of spheroids/2D cell layers using a miniaturized patterned platform as a versatile method to produce scaffold-free tissue engineering building blocks
N.M. Oliveira, C. Martins-Cruz, M.B. Oliveira, R.L. Reis, J.F. Manoc
2018, ADVANCED BIOSYSTEMS, 1700069, 2.
Cell-based microarrays using superhydrophobic platforms patterned with wettable regions
Oliveira, MB; Mano, JF
2018, METHODS IN MOLECULAR BIOLOGY, 1771, 11-26.
Iron Gall Ink Revisited: In Situ Oxidation of Fe(II)-Tannin Complex for Fluidic-Interface Engineering
Lee, H; Kim, WI; Youn, W; Park, T; Lee, S; Kim, TS; Mano, JF; Choi, IS
2018, ADVANCED MATERIALS, 30, 49.
Tuning cell adhesive properties via layer-by-layer assembly of chitosan CrossMark and alginate
Silva, JM; Garcia, JR; Reis, RL; Garcia, AJ; Mano, JF
2017, ACTA BIOMATERIALIA, 51, 279-293.
In vivo osteogenic differentiation of stem cells inside compartmentalized capsules loaded with co-cultured endothelial cells
Correia, CR; Santos, TC; Pirraco, RP; Cerqueira, MT; Marques, AP; Reis, RL; Mano, JF
2017, ACTA BIOMATERIALIA, 53, 483-494.
ISBN:
1878-7568
The influence of surface modified poly(L-lactic acid) films on the differentiation of human monocytes into macrophages
Correia, CR; Gaifem, J; Oliveira, MB; Silvestre, R; Mano, JF
2017, BIOMATERIALS SCIENCE, 5, 3, 551-560.
ISBN:
2047-4849
The potential of cashew gum functionalization as building blocks for layer-by-layer films
Leite, AJ; Costa, RR; Costa, AMS; Maciel, JS; Costa, JFG; de Paula, RCM; Mano, JF
2017, CARBOHYDRATE POLYMERS, 174, 849-857.
ISBN:
1879-1344
The Potential of Liquid Marbles for Biomedical Applications: A Critical Review
Oliveira, NM; Reis, RL; Mano, JF
2017, ADVANCED HEALTHCARE MATERIALS, 6, 19.
ISBN:
2192-2659
Extraction and characterization of collagen from Antarctic and Sub-Antarctic squid and its potential application in hybrid scaffolds for tissue engineering
Coelho, RCG; Marques, ALP; Oliveira, SM; Diogo, GS; Pirraco, RP; Moreira-Silva, J; Xavier, JC; Reis, RL; Silva, TH; Mano, JF
2017, MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 78, 787-795.
ISBN:
1873-0191
Development of a bioactive glass-polymer composite for wound healing applications
Moura, D; Souza, MT; Liverani, L; Rella, G; Luz, GM; Mano, JF; Boccaccini, AR
2017, MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 76, 224-232.
ISBN:
1873-0191
Nacre-inspired nanocomposites produced using layer-by-layer assembly: Design strategies and biomedical applications
Rodrigues, JR; Alves, NM; Mano, JF
2017, MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 76, 1263-1273.
ISBN:
1873-0191
Biomedical applications of natural-based polymers combined with bioactive glass nanoparticles
Leite, AJ; Mano, JF
2017, JOURNAL OF MATERIALS CHEMISTRY B, 5, 24, 4555-4568.
ISBN:
2050-7518
Structural monitoring and modeling of the mechanical deformation of three-dimensional printed poly(epsilon-caprolactone) scaffolds
Ribeiro, JFM; Oliveira, SM; Alves, JL; Pedro, AJ; Reis, RL; Fernandes, EM; Mano, JF
2017, BIOFABRICATION, 9, 2.
ISBN:
1758-5090
Synthesis, mechanical and thermal rheological properties of new gellan gum derivatives
Agnello, S; Gasperini, L; Mano, JF; Pitarresi, G; Palumbo, FS; Reis, RL; Giammona, G
2017, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 98, 646-653.
ISBN:
1879-0003
Solvent-Free Strategy Yields Size and Shape-Uniform Capsules
Costa, AMS; Mano, JF
2017, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 139, 3, 1057-1060.
Flexible method for fabricating protein patterns on superhydrophobic platforms controlled by magnetic field
Wang, J; Li, H; Zou, HY; Wang, CM; Zhang, H; Mano, JF; Song, WL
2017, BIOMATERIALS SCIENCE, 5, 3, 408-411.
ISBN:
2047-4849
Nanostructured interfacial self-assembled peptide-polymer membranes for enhanced mineralization and cell adhesion
Ribeiro, S; Radvar, E; Shi, Y; Borges, J; Pirraco, RP; Leonor, IB; Mano, JF; Reis, RL; Mata, A; Azevedo, HS
2017, NANOSCALE, 9, 36, 13670-13682.
ISBN:
2040-3372
Nanoengineering Hybrid Supramolecular Multilayered Biomaterials Using Polysaccharides and Self-Assembling Peptide Amphiphiles
Borges, J; Sousa, MP; Cinar, G; Caridade, SG; Guler, MO; Mano, JF
2017, ADVANCED FUNCTIONAL MATERIALS, 27, 17.
ISBN:
1616-3028
Multilayered membranes with tuned well arrays to be used as regenerative patches
Martins, NI; Sousa, MP; Custodio, CA; Pinto, VC; Sousa, PJ; Minas, G; Cleymand, F; Mano, JF
2017, ACTA BIOMATERIALIA, 57, 313-323.
ISBN:
1878-7568
Control of Cell Alignment and Morphology by Redesigning ECM-Mimetic Nanotopography on Multilayer Membranes
Sousa, MP; Caridade, SG; Mano, JF
2017, ADVANCED HEALTHCARE MATERIALS, 6, 15.
ISBN:
2192-2659
Screening of Nanocomposite Scaffolds Arrays Using Superhydrophobic-Wettable Micropatterns
Leite, AJ; Oliveira, MB; Caridade, SG; Mano, JF
2017, ADVANCED FUNCTIONAL MATERIALS, 27, 28.
ISBN:
1616-3028
Layered PEGDA hydrogel for islet of Langerhans encapsulation and improvement of vascularization
Marchioli, G; Zellner, L; Oliveira, C; Engelse, M; de Koning, E; Mano, J; Karperien; van Apeldoorn, A; Moroni, L
2017, JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 28, 12.
Engineering Membranes for Bone Regeneration
Caridade, SG; Mano, JF
2017, TISSUE ENGINEERING PART A, 23, 23-24, 1502-1533.
Development and Characterization of Free Standing Biomembranes for Tissue Engineering Applications
Cleymand, F; Fleutot, S; Mano, JF
2017, TISSUE ENGINEERING PART A, 23, S34-S34.
Development Of A Textured Patch for the Engineering of Heart Tissues
Cleymand, F; Robin, J; Nguyen, T; Menu, P; Mano, JF
2017, TISSUE ENGINEERING PART A, 23, S23-S24.
Freestanding Multilayered Membranes patterned with Micro-Reservoirs as potential Regenerative Paths
Sousa, MP; Martins, NI; Custodio, CA; Pinto, VC; Sousa, PJ; Minas, G; Cleymand, F; Mano, JF
2017, TISSUE ENGINEERING PART A, 23, S55-S55.
Bioinspired Ultratough Hydrogel with Fast Recovery, Self-Healing, Injectability and Cytocompatibility
Azevedo, S; Costa, AMS; Andersen, A; Choi, IS; Birkedal, H; Mono, JF
2017, ADVANCED MATERIALS, 29, 28.
Eco-friendly sol-gel derived sodium-based ormolytes for electrochromic devices
Fernandes, M; Leones, R; Pereira, S; Costa, AMS; Mano, JF; Silva, MM; Fortunato, E; Bermudez, VD; Rego, R
2017, ELECTROCHIMICA ACTA, 232, 484-494.
Open Fluidics: A Cell Culture Flow System Developed Over Wettability Contrast-Based Chips
Oliveira, NM; Reis, RL; Mano, JF
2017, ADVANCED HEALTHCARE MATERIALS, 6, 24.
Advanced Control over Cell-Material Interfaces
Mano, JF; Choi, IS
2017, POLYMERS, 9, 12.
Mesenchymal Stem Cells Relevance in Multicellular Bioengineered 3D In Vitro Tumor Models
Ferreira, LP; Gaspar, VM; Henrique, R; Jeronimo, C; Mano, JF
2017, BIOTECHNOLOGY JOURNAL, 12, 12.
Extracellular vesicles, exosomes and shedding vesicles in regenerative medicine - a new paradigm for tissue repair
Bjorge, IM; Kim, SY; Mano, JF; Kalionis, B; Chrzanowski, W
2017, BIOMATERIALS SCIENCE, 6, 1, 60-78.
Cell-Adhesive Bioinspired and Catechol-Based Multilayer Freestanding Membranes for Bone Tissue Engineering
Sousa, MP; Mano, JF
2017, BIOMIMETICS, 2, 4.
Bottom-up fabrication of hybrid polysaccharide/peptide amphiphile supramolecular multilayered biomaterials by combining self-assembly and layer-by-layer assembly approaches
Borges, J; Sousa, M; Cinar, G; Caridade, S; Guler, M; Mano, J
2017, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 253.
Free-standing multilayered membranes from renewable polymers, towards tissue engineering applications
Sousa, M; Cleymand, F; Mano, J
2017, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 253.
Biomimetic click assembled multilayer coatings exhibiting responsive properties
Sousa, MP; de Torre, IG; Oliveira, MB; Rodriguez-Cabello, JC; Mano, JF
2017, MATERIALS TODAY CHEMISTRY, 4, 150-163.
Biomimetic Interfaces in Biomedical Devices
Mano, JF; Choi, IS; Khademhosseini, A
2017, ADVANCED HEALTHCARE MATERIALS, 6, 15.
Multiscale characterization of the hierarchical structure of Dynastes hercules elytra
Roux-Pertus, C; Oliviero, E; Viguier, V; Fernandez, F; Maillot, F; Ferry, O; Fleutot, S; Mano, JF; Cleymand, F
2017, MICRON, 101, 16-24.
AFOB Special Issue on Stem Cells in Tissue Engineering and Regenerative Medicine
Sakai, S; Mano, JF
2017, BIOTECHNOLOGY JOURNAL, 12, 12.
Investigating the effect of fibulin-1 on the differentiation of human nasal inferior turbinate-derived mesenchymal stem cells into osteoblasts
Pham, LBH; Yoo, YR; Park, SH; Back, SA; Kim, SW; Bjorge, I; Mano, J; Jang, JH
2017, JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 105, 8, 2291-2298.
Bioplotting of a bioactive alginate dialdehyde-gelatin composite hydrogel containing bioactive glass nanoparticles
Álvaro J Leite, Bapi Sarker, Tobias Zehnder, Raquel Silva, João F Manoand Aldo R Boccaccini
2016, Biofabrication, 8, 3.
Cell Surface Engineering to Control Cellular Interactions
Custodio, CA; Mano, JF
2016, CHEMNANOMAT, 2, 5, 376-384.
Coating Strategies Using Layer-by-layer Deposition for Cell Encapsulation
Oliveira, MB; Hatami, J; Mano, JF
2016, CHEMISTRY-AN ASIAN JOURNAL, 11, 12, 1753-1764.
Design Advances in Particulate Systems for Biomedical Applications
Lima, AC; Alvarez-Lorenzo, C; Mano, JF
2016, ADVANCED HEALTHCARE MATERIALS, 5, 14, 1687-1723.
Effect of Polyelectrolyte Multilayers Assembled on Ordered Nanostructures on Adhesion of Human Fibroblasts
Niepel, MS; Mano, JF; Groth, T
2016, ACS APPLIED MATERIALS & INTERFACES, 8, 38, 25142-25151.
Elastic chitosan/chondroitin sulfate multilayer membranes
Sousa, MP; Cleymand, F; Mano, JF
2016, BIOMEDICAL MATERIALS, 11, 3.
Fabrication of Hydrogel Particles of Defined Shapes Using Superhydrophobic-Hydrophilic Micropatterns
Neto, AI; Demir, K; Popova, AA; Oliveira, MB; Mano, JF; Levkin, PA
2016, ADVANCED MATERIALS, 28, 35, 7613-+.
Membranes combining chitosan and natural-origin nanoliposomes for tissue engineering
Cleymand, F; Zhang, HY; Dostert, G; Menu, P; Arab-Tehrany, E; Velot, E; Mano, JF
2016, RSC ADVANCES, 6, 87, 83626-83637.
Multilayered Hollow Tubes as Blood Vessel Substitutes
Silva, JM; Custodio, CA; Reis, RL; Mano, JF
2016, ACS BIOMATERIALS SCIENCE & ENGINEERING, 2, 12, 2304-2314.
Morphology and miscibility of chitosan/soy protein blended membranes
Silva, SS; Goodfellow, BJ; Benesch, J; Rocha, J; Mano, JF; Reis, RL
2007, CARBOHYDRATE POLYMERS, 70, 1, 25-31.
Functional nanostructured chitosan-siloxane hybrids
Silva, SS; Ferreira, RAS; Fu, LS; Carlos, LD; Mano, JF; Reis, RL; Rocha, J
2005, JOURNAL OF MATERIALS CHEMISTRY, 15, 35-36, 3952-3961.
